Job Opportunity: Scientist – Small Molecule Technology at Pfizer

Job Summary

Pfizer is seeking a highly skilled and motivated Scientist – Small Molecule Technology to join our Research & Development team in Chennai, India. This role is designed for PhD professionals with a passion for innovation in API process development. You will play a critical role in advancing our small molecule drug pipelines by leading process optimization, scale-up efforts, and technology transfer from the lab to GMP manufacturing. If you are an expert in organic synthesis looking to make a global impact on life-saving medicines, we invite you to apply.

Key Responsibilities

As a Scientist at Pfizer, you will be at the forefront of pharmaceutical innovation. Your daily responsibilities will include:

• Process Development: Conduct literature searches to identify optimal synthetic routes for APIs, intermediates, and regulatory starting materials (RSMs).
• Optimization & Innovation: Lead process development initiatives to improve yields, reduce costs, and drive innovation within small molecule chemistry.
• Experimental Design: Design and execute Design of Experiments (DoE) to ensure robust, reproducible process development.
• Lab Operations: Conduct feasibility, optimization, pre-validation, and validation studies while managing lab inventory and equipment qualification.
• Technology Transfer: Facilitate the seamless transition of processes to manufacturing scale and provide technical support to resolve scale-up challenges or process deviations.
• Characterization: Develop and characterize process-related impurities to maintain high quality standards.
• Compliance & Documentation: Ensure all activities strictly adhere to cGMP guidelines and safety procedures. Prepare detailed scientific reports, protocols, and essential tech transfer documentation.

Qualifications Required

We are looking for candidates who combine academic excellence with practical industrial experience:

• Education: A PhD in Chemistry is mandatory.
• Technical Expertise: Deep knowledge of organic synthesis, reaction mechanisms, and API process development. Proficiency in analytical characterization techniques is essential.
• Regulatory Knowledge: Solid understanding of cGMP guidelines, process validation, Critical Process Parameters (CPP), and industrial scale-up procedures.
• Professional Skills: Excellent scientific writing and documentation skills, coupled with the ability to collaborate effectively in cross-functional teams and solve complex technical problems.

Preferred Skills:

• Prior experience in small molecule drug development and impurity profiling.
• Hands-on exposure to MS&T (Manufacturing Science and Technology), Kilo Lab, or Pilot Plant operations.

Why Join Pfizer?

Working at Pfizer means joining a global leader dedicated to creating breakthroughs that change patients’ lives. As a member of our team, you will benefit from:

• Global Exposure: Involvement in cutting-edge pharmaceutical R&D on a worldwide scale.
• Professional Growth: A research-driven environment that provides access to advanced technologies and high-level training.
• Meaningful Work: The opportunity to contribute directly to the development of life-saving medicines.
• Collaborative Culture: A supportive and innovative team environment that encourages scientific curiosity and career advancement.

Position Details

• Role: Scientist – Small Molecule Technology
• Department: Research & Development
• Location: Chennai, India
• Job Type: Full-Time (On-site)
• Compensation: ₹12 LPA – ₹22 LPA (commensurate with experience and expertise)

How to Apply

If you meet the requirements and are eager to advance your career with a world-class pharmaceutical company, please submit your application through the official Pfizer careers portal:

Click Here to Apply on the Pfizer Careers Website

Pfizer is an equal opportunity employer. We value diversity and are committed to creating an inclusive environment for all employees.