Job Title: Oligonucleotide Synthesis Scientist – Shape the Future of Nucleic Acid Therapeutics
Summary:
Barcode Biosciences Pvt Ltd, a rapidly expanding force in the oligonucleotide and nucleic acid therapeutics industry, is seeking highly motivated and talented MSc graduates to join our dynamic Oligonucleotide Synthesis team in Bengaluru. This is an exceptional opportunity for a passionate and driven individual with a background in Chemistry, Biochemistry, or Biotechnology to contribute to cutting-edge research and development in DNA/RNA synthesis and build a rewarding career within a thriving biotech environment. If you are a recent graduate eager to apply your knowledge and skills to the advancement of healthcare, we encourage you to apply.
About Barcode Biosciences:
At Barcode Biosciences, we are dedicated to innovation and excellence in the development and manufacturing of oligonucleotides for therapeutic applications. We foster a collaborative and stimulating work environment where every team member is empowered to make a significant impact. We offer a competitive compensation package, opportunities for professional growth, and a chance to be part of a team that is shaping the future of medicine.
Job Description:
As an Oligonucleotide Synthesis Scientist, you will play a vital role in the production of high-quality oligonucleotides used in research, diagnostics, and therapeutic applications. You will be responsible for performing solid-phase oligonucleotide synthesis, purification, and quality control, ensuring that all processes adhere to the highest industry standards.
Key Responsibilities:
- Oligonucleotide Synthesis: Perform solid-phase oligonucleotide synthesis utilizing automated synthesizers, adhering to established protocols and optimizing processes for efficiency and yield.
- Deprotection, Cleavage, and Purification: Execute deprotection, cleavage, and purification of synthesized oligonucleotides using techniques such as High-Performance Liquid Chromatography (HPLC) and Polyacrylamide Gel Electrophoresis (PAGE).
- Documentation and Record Keeping: Maintain meticulous batch records and documentation, ensuring compliance with Good Manufacturing Practice (GMP) and Good Laboratory Practice (GLP) standards.
- Process Optimization: Support scale-up activities and contribute to the optimization of synthesis processes to improve efficiency, reduce costs, and enhance product quality.
- Instrument Maintenance: Perform routine instrument calibration and maintenance to ensure the proper functioning of synthesis equipment and analytical instruments.
- Quality Assurance: Collaborate closely with QC and analytical teams to ensure the quality and integrity of synthesized oligonucleotides, contributing to the overall quality assurance process.
- Problem Solving: Troubleshoot issues during synthesis and purification, identifying root causes and implementing solutions to ensure the smooth operation of processes.
- Continuous Improvement: Stay up-to-date with the latest advancements in oligonucleotide synthesis and purification techniques, and actively contribute to the development and implementation of new and improved protocols.
Eligibility & Qualifications:
- Education: MSc in Chemistry, Organic Chemistry, Biochemistry, or Biotechnology (graduating class of 2023-2025).
- Experience: 0-1 year of hands-on experience (academic project or internship in oligonucleotide/peptide synthesis is highly desirable).
- Knowledge: Strong theoretical and practical knowledge of organic and phosphoramidite chemistry is essential.
- Technical Skills: Familiarity with HPLC, UV spectroscopy, and MALDI-TOF is preferred.
- Soft Skills: Excellent learning attitude, problem-solving skills, attention to detail, and the ability to work effectively both independently and as part of a team are crucial.
- Communication Skills: Strong written and verbal communication skills are required for documentation, presentations, and collaboration with other team members.
Benefits & Perks:
- Competitive Salary: A competitive salary package ranging from ₹4.8 – 6.8 LPA, representing the best in the industry for fresh graduates.
- Comprehensive Benefits: Health insurance and accidental coverage to ensure your well-being.
- Convenient Amenities: Cab facility and subsidized meals for a comfortable and convenient work experience.
- Career Growth: Fast-track growth opportunities, with multiple employees receiving promotions within 12-18 months.
- Exposure to Cutting-Edge Technology: Opportunity to work with the latest automated oligo synthesizers and contribute to global projects.
- Professional Development: Opportunities for training and development to enhance your skills and knowledge.
How to Apply:
If you are a highly motivated and talented individual seeking an exciting opportunity to contribute to the field of oligonucleotide synthesis, we encourage you to apply. Please submit your updated resume with a cover letter highlighting your relevant skills and experience to [email protected]. In the subject line of your email, please write “Application – Oligonucleotide Synthesis Scientist.”
Application Deadline: January 4, 2026
We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.
We look forward to receiving your application and welcoming you to the Barcode Biosciences team!