Job Opportunity: Manager – R&D (Downstream Processing & Protein Chemistry)

Job Summary

Ichor Biologics is seeking a highly skilled and experienced Manager for our R&D Downstream Processing team in Hyderabad. This leadership role is designed for professionals with a deep expertise in biologics and protein purification who are eager to contribute to the advancement of plasma-derived medicinal products (PDMPs). As we expand our R&D capabilities, you will play a pivotal role in optimizing protein development processes, ensuring manufacturing robustness, and overseeing the transition from laboratory scale to full commercial production. This is an exceptional opportunity to drive technical excellence in a collaborative, innovation-focused environment.

Job Overview

• Location: Hyderabad, India
• Sector: Biologics / Plasma-Derived Medicinal Products (PDMP)
• Role Type: R&D Leadership / Management

Responsibilities

Downstream Processing & Purification

• Design, develop, and optimize robust protein purification processes, utilizing advanced chromatography techniques, Tangential Flow Filtration (TFF), and various filtration methodologies.
• Apply advanced principles of protein chemistry to enhance protein yield, purity, stability, and overall product quality.

Scale-Up & Technology Transfer

• Lead the seamless transition of processes from lab-scale and pilot-plant stages to full-scale commercial manufacturing.
• Direct end-to-end technology transfer activities, ensuring all processes are scalable, efficient, and reproducible.

Troubleshooting & Manufacturing Support

• Act as a technical subject matter expert to resolve complex issues during manufacturing, including yield loss, protein aggregation, impurity profiles, and process variability.
• Provide ongoing scientific guidance and support to Drug Substance (DS) manufacturing operations to maintain high performance and quality standards.

Documentation & Regulatory Compliance

• Author and review technical R&D protocols, detailed scientific reports, and essential regulatory documentation.
• Design and execute comprehensive process characterization and comparability studies to meet global regulatory requirements.

Cross-Functional Collaboration

• Partner effectively with internal teams—including Manufacturing, Manufacturing Science and Technology (MSAT), Analytical Research and Development (ARD), and Quality Assurance (QA)—to implement sustainable, compliant, and efficient production solutions.

Requirements

Educational Qualifications

• M.Sc. in Biotechnology, Biochemistry, Chemical Engineering, or a related field with 12–15 years of relevant industry experience.
• OR Ph.D. in Biotechnology, Biochemistry, Chemical Engineering, or a related field with 6–7 years of relevant industry experience.

Skills & Expertise

• Proven technical expertise in downstream processing and protein purification within the biologics industry.
• Strong track record of providing hands-on support for commercial-scale manufacturing over the past 5–7 years.
• Comprehensive understanding of current regulatory guidelines and quality standards in the pharmaceutical/biotech sector.
• Exceptional problem-solving abilities with a detail-oriented approach to process development.
• Demonstrated ability to function effectively in both laboratory research settings and large-scale manufacturing environments.

Benefits

• Competitive Compensation: An annual salary range of ₹18,00,000 – ₹32,00,000, commensurate with your experience and qualifications.
• Professional Growth: Opportunity to lead projects on cutting-edge plasma-derived medicinal products and gain significant exposure to commercial-scale manufacturing.
• Innovation Culture: Work in a supportive environment that prioritizes scientific advancement and cross-functional teamwork.
• Global Exposure: Gain experience working with global quality and manufacturing standards.

How to Apply

We invite qualified candidates to submit an updated resume to [email protected]. Please ensure your application highlights your experience in downstream processing and commercial manufacturing support.

Ichor Biologics is an equal opportunity employer. We encourage you to share this opportunity with your professional network.