Scientist – Research Computational Biology (ARIA)
Amgen is seeking a highly motivated and skilled Scientist to join our ARIA (AI-Driven Research and Analytics) Computational Biology team in Hyderabad. This role offers an exciting opportunity to contribute to target discovery, disease endotype characterization, and the advancement of our therapeutic pipeline. If you are passionate about leveraging computational biology and AI to drive groundbreaking research and develop next-generation therapeutics, we encourage you to apply.
Job Summary
As a Scientist in the ARIA Computational Biology team, you will be responsible for extracting biological insights from multi-modal omics and screening data. You will play a crucial role in characterizing disease endotypes and identifying novel therapeutic targets. This position requires strong analytical skills, proficiency in programming languages, and the ability to collaborate effectively with cross-functional teams.
Responsibilities
- Extract biological insights from multi-modal omics and screening data.
- Characterize disease endotypes, mechanisms, and novel therapeutic targets.
- Develop platforms for target prioritization across diseases and therapeutic areas.
- Analyze RNA and protein isoform complexity using long-read transcriptomics and proteomics.
- Build advanced capabilities for discovering disease-enriched isoforms.
- Collaborate with data science and IS teams to integrate computational tools into Amgen’s R&D platforms.
- Develop automated pipelines, interactive portals, and workflows (Nextflow, RShiny).
Requirements
- Education:
- Ph.D. in Computational Biology, Bioinformatics, or Data Science, OR
- Master’s degree + 3 years of relevant research experience
- Technical Skills:
- Strong proficiency in Python, R, Linux/Unix, HPC, and Git.
- Proven track record in single-cell omics analytics.
- Experience:
- Experience designing holistic computational research strategies.
- Soft Skills:
- Excellent communication and presentation skills.
- Self-driven and collaborative mindset.
Preferred Qualifications
- Strong immunology expertise (oncology/inflammatory disease context).
- Deep understanding of isoform biology and long-read sequencing analytics.
- Experience with foundation models and biomedical knowledge graphs.
- Familiarity with datasets like DepMap, HCA, TCGA, GTEx, and Tahoe-100M.
- Experience deploying tools to RShiny, Nextflow, interactive portals, and agentic systems.
Benefits of Joining Amgen ARIA
- Work on cutting-edge computational biology research.
- Opportunities for global collaboration.
- Access to modern research infrastructure & cloud environments.
- Excellent learning and leadership growth pathways.
- Competitive compensation and employee benefits.
- Chance to contribute to the development of next-generation therapeutics.
Job Details
- Role: Scientist – Research Computational Biology (ARIA)
- Company: Amgen
- Location: Hyderabad, India (On-site)
- Employment Type: Full Time
- Category: Research / Computational Biology
How to Apply
If you meet the qualifications and are excited about the opportunity to contribute to innovative research at Amgen, we encourage you to apply. Please submit your application through our online portal. We look forward to hearing from you.